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Renal disease and rheumatic manifestations
1Department of Rheumatology, Royal North Shore Hosital, Sydney, Australia.
Current Opinion in Rheumatology
|January 1, 1993
Summary
Renal disease can cause rheumatic issues. Modern therapies like dialysis and transplantation lead to new bone, joint, and soft tissue disorders, including ligament laxity and avascular necrosis.
Area of Science:
- Rheumatology
- Nephrology
- Orthopedics
Background:
- Renal disease is a known cause of rheumatic complaints.
- Renal replacement therapies (dialysis, transplantation) introduce new musculoskeletal issues.
- Musculoskeletal complications impact patients with chronic kidney disease.
Purpose of the Study:
- To review the spectrum of rheumatic disorders associated with renal disease and its treatments.
- To highlight the prevalence of specific musculoskeletal conditions in dialysis and transplant patients.
- To discuss the natural history of avascular necrosis post-renal transplantation.
Main Methods:
- Literature review of recent surveys and studies.
- Analysis of data on ligamentous laxity in transplant recipients.
- Examination of studies on dialysis-associated arthropathy.
- Investigation into avascular necrosis in early post-transplant phase.
Main Results:
- High prevalence of ligamentous laxity observed in renal transplant patients.
- Dialysis-associated arthropathy is common in long-term dialysis patients.
- Avascular necrosis is a significant concern in the early post-transplant period.
Conclusions:
- Renal replacement therapy shifts the landscape of rheumatic complaints.
- Musculoskeletal health requires careful monitoring in patients with renal disease undergoing treatment.
- Further research into the pathogenesis and management of these disorders is warranted.