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Related Experiment Videos

Reversible diencephalic dysfunction: episodic hyperhidrosis due to a trapped third ventricle

R B Darnell1, E Arbit

  • 1Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY.

Neurology
|March 1, 1993
PubMed
Summary
This summary is machine-generated.

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Episodic hyperhidrosis (EH) linked to isolated third ventricle was resolved by stereotactic shunting. This suggests periodic third ventricular pressure increases cause diencephalic dysfunction and EH.

Area of Science:

  • Neurology
  • Neurosurgery
  • Endocrinology

Background:

  • Episodic hyperhidrosis (EH) is a condition characterized by recurrent episodes of excessive sweating.
  • The causes of EH are diverse, often involving autonomic nervous system dysfunction.

Observation:

  • A patient presented with frequent daily episodes of EH lasting for 3 years after lateral ventricular shunt placement.
  • Magnetic Resonance Imaging (MRI) identified an isolated third ventricle in the patient.

Findings:

  • Stereotactic shunting of the third ventricle led to immediate and complete resolution of the patient's hyperhidrosis symptoms.
  • The findings suggest a causal link between third ventricular pressure dynamics and EH.

Implications:

Related Experiment Videos

  • This case highlights a potential mechanism for EH involving elevated third ventricular pressure and subsequent diencephalic dysfunction.
  • Stereotactic third ventricular shunting may be an effective treatment for specific cases of refractory episodic hyperhidrosis.