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Implications of coronary angiography in patients with suspected or known coronary artery disease
A K Pande1, B Meier, W Rutishauser
1Cardiology Center, University Hospital, Geneva, Switzerland.
Insights
This study on 500 patients found that coronary artery disease (CAD) is prevalent, with significant lesions affecting over half of those undergoing coronary angiography. Findings inform treatment strategies for coronary lesions and CAD.
Area of Science:
- Cardiology
- Interventional Cardiology
- Diagnostic Imaging
Background:
- Coronary artery disease (CAD) remains a leading cause of mortality worldwide.
- Accurate assessment of coronary lesions is crucial for effective treatment planning.
- Coronary angiography is a primary diagnostic tool for evaluating CAD.
Purpose of the Study:
- To analyze the incidence and patterns of coronary lesions in patients undergoing coronary angiography.
- To evaluate the implications of these lesions on treatment strategies.
- To provide data on the prevalence of single-vessel, two-vessel, and three-vessel disease.
Main Methods:
- Retrospective analysis of 500 consecutive patients undergoing coronary angiography.
- Exclusion of patients with congenital heart disease, pure valve disease, or cardiomyopathy.
- Detailed assessment of coronary artery anatomy, lesion severity, and prior cardiac procedures.
Main Results:
- 12% had normal coronary arteries, 14% had non-significant lesions.
- Significant coronary lesions were found in 74% of patients.
- One-vessel disease (34%), two-vessel disease (19%), and three-vessel disease (18%) were common.
- Left main coronary artery disease was present in 3% of patients.
Conclusions:
- Coronary angiography reveals a high incidence of significant coronary lesions in patients with suspected or confirmed CAD.
- Understanding the distribution of coronary lesions is vital for guiding revascularization decisions.
- The study highlights the importance of detailed angiographic analysis for patient management.
Abstract:
The study analyzes the incidence of coronary lesions and their implications on the treatment offered in 500 consecutive non-selected patients (406 males (81%), age 60 +/- 10 (+/- 1 standard deviation), range 21-88 years) undergoing coronary angiography for suspicion or confirmation of coronary artery disease (excluding patients with congenital and pure valve disease, or cardiomyopathy). A history of myocardial infarction was present in 205 patients (41%). There were no prior cardiac procedures in 334 patients (67%). There was prior coronary angioplasty in 82 patients (16%), coronary artery bypass grafting in 44 (9%) and both in 4 (1%). A total of 36 patients (7%) had had prior coronary angiography only. Mean left ventricular ejection fraction was 61 +/- 12 (18-83%) and mean left ventricular end diastolic pressure was 12 +/- 6 (2-37) mmHg. Angiographically normal coronary arteries were present in 61 patients (12%) and non-significant coronary lesions in 70 patients (14%). One vessel disease was present in 169 patients (34%), two vessel disease in 97 (19%), three vessel disease in 88 (18%) and left main coronary artery disease in 15 (3%). In single vessel disease, involvement of the left anterior descending coronary artery was seen in 82 patients (49%), left circumflex coronary artery in 38 (22%) and right coronary artery in 49 (29%). In two vessel disease, involvement of the left anterior descending coronary artery and left circumflex coronary artery was present in 30 patients (31%), left anterior descending coronary artery and right coronary artery in 36 (37%) and left circumflex coronary artery and right coronary artery in 31 (32%).(ABSTRACT TRUNCATED AT 250 WORDS)
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