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Cytotoxicity of some modified root canal sealers and their leachable components
S V Barbosa1, K Araki, L S Spångberg
1University of Connecticut Health Center, Farmington.
Oral Surgery, Oral Medicine, and Oral Pathology
|March 1, 1993
Abstract:
The toxic effects of modified endodontic sealers, Fillcanal, N-Rickert, FS, and Sealer 26, were assessed. The material toxicity was measured through radiochromium release method that uses direct and indirect contact methods. The sealers were evaluated freshly mixed and after various setting times. L929 mouse and periodontal ligament fibroblast cells were used as target cells. Fillcanal, N-Rickert, and FS showed high toxicity. Fillcanal leaches toxic material when fresh and after setting time. Sealer 26 was the least toxic.