[Pathologic karyotypes in autopsy material]

In 1986-1989 the authors were concerned with the cultivation of necroptic material. Material was collected from five indication groups outlined in advance. A total of 231 specimens of necroptic material were cultivated, incl. 143 specimens subjected to cytological evaluation. From the above material 20 pathological karyotypes were diagnosed. The results of cytogenetic analysis of chromosome abnormalities were compared with the clinical and pathological diagnosis. Post-mortem chromosome analysis is important for elucidation of the aetiopathogenesis of perinatal deaths and for a comprehensive approach to families with genetic risk.