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Related Experiment Videos

Automated biopsy devices: a blinded evaluation

K D Hopper1, C S Abendroth, K W Sturtz

  • 1Department of Radiology, Penn State University, Hershey 17033.

Radiology
|June 1, 1993
PubMed
Summary
This summary is machine-generated.

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Automated biopsy devices with a 2.0 cm excursion provide high-quality tissue for histopathologic analysis. Long-throw biopsy guns performed best, while short-throw devices yielded suboptimal results.

Area of Science:

  • Histopathology
  • Medical Devices
  • Surgical Pathology

Background:

  • Automated biopsy devices are crucial for obtaining tissue samples for histopathologic analysis.
  • Evaluating the performance of different automated biopsy devices is essential for optimizing diagnostic accuracy.

Purpose of the Study:

  • To compare the quality of tissue specimens obtained from 20 different 18-gauge automated biopsy devices.
  • To identify automated biopsy devices that yield high-quality tissue with minimal artifacts for histopathologic analysis.

Main Methods:

  • 1,470 biopsy specimens were obtained from 10 fresh autopsy cases using 20 different 18-gauge automated biopsy devices.
  • Biopsies were performed on liver, kidney, pancreas, and psoas muscle at various depths.
  • Tissue quality was assessed based on specimen size, fragmentation, and crush artifact.

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Main Results:

  • No statistical difference in performance was observed among five long-throw biopsy guns (Biopty, ASAP 18, UltraCut, Monopty, ABS) that yielded large tissue amounts with minimal artifacts.
  • Most short-throw biopsy guns (biopsy depth <= 1.1 cm) performed less effectively.
  • Several devices (Temno, Bio-Gun, Roth, Klear Kut, ABC, Urocut) provided less than optimal results.

Conclusions:

  • 18-gauge automated biopsy devices with a biopsy excursion of at least 2.0 cm consistently provide high-quality, diagnostically adequate specimens.
  • Long-throw automated biopsy devices are recommended for optimal tissue acquisition in histopathologic analysis.