Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Slow-release fluoride

K J Toumba1, M E Curzon

  • 1Department of Paediatric Dentistry, Leeds Dental Institute, UK.

Caries Research
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Frequent, low-concentration fluoride applications, especially via novel intra-oral devices, effectively combat caries. These devices increase fluoride levels and uptake, showing promise for high-risk populations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Guidelines on the use of fluoride for caries prevention in children: an updated EAPD policy document.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2019
Same author

The effect on dental enamel of the frequency of consumption of fluoridated milk with a cariogenic challenge in situ.

Journal of dentistry·2018
Same author

Regional Odontodysplasia with Generalised Enamel Defect.

Case reports in dentistry·2017
Same author

Fluoride levels in UK infant milks.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2016
Same author

Comparison of residual salivary fluoride retention using amine fluoride toothpastes in caries-free and caries-prone children.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2016
Same author

European Academy of Paediatric Dentistry guideline production.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2016
Same journal

Artificial Intelligence in Caries Risk Assessment: Evaluating the Current Status of CAMBRA and Cariogram with Large Language Models.

Caries research·2026
Same journal

AI-Driven Decision Thresholds in Cariology: A Systematic Review of Lesion Stage Detection on Bitewing Radiographs.

Caries research·2026
Same journal

What is dental caries - and why we need fluoride.

Caries research·2026
Same journal

Does adolescent obesity influence caries increment among young adults? A 5-year cohort study in southern Brazil.

Caries research·2026
Same journal

Teaching Others, Reflecting Self: Does Educating Patients Impact Students' Own Plaque Control?

Caries research·2026
Same journal

Deep Caries Management: EFCD-ESE-ORCA S3-Level Clinical Practice Guideline.

Caries research·2026
See all related articles

Area of Science:

  • Dental Science
  • Caries Prevention
  • Biomaterials

Background:

  • Traditional fluoride applications face challenges with short-lived release from dental materials.
  • Frequent, low-dose fluoride is increasingly supported for caries elimination, even in high-risk scenarios.

Purpose of the Study:

  • To evaluate the efficacy of intra-oral fluoride-releasing devices for caries prevention.
  • To assess the long-term fluoride release and uptake potential of novel dental materials.

Main Methods:

  • Development and testing of intra-oral devices (copolymer membranes, glass devices) for sustained fluoride delivery.
  • Animal studies (rats) and ongoing human clinical trials to assess caries reduction and fluoride levels.

Main Results:

Related Experiment Videos

  • Intra-oral devices elevate salivary fluoride levels for up to two years in both animal and human subjects.
  • Increased fluoride uptake in enamel has been observed with these devices.
  • Caries reduction was demonstrated in rats using the copolymer device.

Conclusions:

  • Intra-oral fluoride-releasing devices offer a promising strategy for sustained caries prevention.
  • These devices have the potential to significantly improve oral health outcomes in high-caries-risk populations.
  • Targeted application in low socio-economic groups, ethnic minorities, and individuals with disabilities is a key potential benefit.