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Systemic fluorides: drops and tablets

K W Stephen1

  • 1Department of Oral Medicine and Pathology, University of Glasgow Dental School, UK.

Caries Research
|January 1, 1993
PubMed
Summary
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Fluoride drops and tablets effectively prevent cavities topically. While home and school use effectiveness varies, daily low-dose fluoride from birth shows no link to dental fluorosis.

Area of Science:

  • Dentistry
  • Public Health
  • Pharmacology

Background:

  • Fluoride drops and tablets are widely used for caries prevention.
  • Their efficacy is influenced by administration methods and compliance.
  • Previous studies on prenatal fluoride supplementation lacked robust methodology.

Purpose of the Study:

  • To evaluate the effectiveness of fluoride drops and tablets in caries inhibition.
  • To assess the impact of compliance on caries prevention outcomes.
  • To investigate the association between prenatal fluoride exposure and dental fluorosis.

Main Methods:

  • Review of caries trials involving home and school-based fluoride drop/tablet use.
  • Analysis of double-blind studies on prenatal fluoride tablet administration.

Related Experiment Videos

  • Assessment of fluorosis prevalence in relation to early-life fluoride dosage.

    • Main Results:

    • Home and school-based fluoride delivery showed variable caries reductions (20-80%+), linked to compliance and vigilance.
    • Prenatal fluoride tablet use demonstrated a non-significant positive trend for caries prevention.
    • A daily 0.25 mg fluoride dose from birth was not associated with increased dental fluorosis when other fluoride products were used judiciously.

    Conclusions:

    • Fluoride drops and tablets offer topical benefits for individual caries prevention, particularly for children and adolescents.
    • Community-level impact of fluoride supplements is less comparable to water or salt fluoridation.
    • Judicious use of fluoride supplements from birth, at recommended doses, does not elevate fluorosis risk.