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Summary
Malacoplakia of the kidney is not benign. Bilateral renal parenchymal malacoplakia is fatal, indicating a poor prognosis for this rare condition.
Area of Science:
- Nephrology
- Pathology
Background:
- Malacoplakia is typically considered a benign condition.
- Renal involvement is rare but can have serious implications.
Purpose of the Study:
- To investigate the clinical and pathologic features of renal parenchymal malacoplakia.
- To determine the prognosis of this renal disease.
Main Methods:
- Review of literature.
- Analysis of recent clinical experience with renal malacoplakia.
Main Results:
- Upper urinary tract malacoplakia is not benign or self-limited.
- Bilateral renal parenchymal malacoplakia has a uniformly fatal outcome.
Conclusions:
- Renal parenchymal malacoplakia requires careful consideration due to its potentially severe course.
- The prognosis is poor, especially with bilateral involvement.