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[Storage of thrombocyte concentrates: quality control by in vitro bleeding test]
A Glaser1, M Böck, G Rüschemeyer
1Tranfusionzentrum (Med. Klinik III) Klinikum Grosshadern, Universität München.
Background:
The increasing demand for single-donor platelet concentrates necessitates the storage of these blood products prior to transfusion. Quality control of these platelets, however, is still a problem. Most of the available techniques are time-consuming and require sophisticated equipment and specifically trained personnel. The present paper describes a new method for quality control of stored platelet concentrates.
Materials And Methods:
Single-donor platelet concentrates were stored for 7 days; daily aliquots were taken and the in vitro bleeding time (Thrombostat 4000) and platelet aggregation (aggregometer) were determined.
Results:
The in vitro bleeding test can be handled simply and fast. The results are comparable with those of platelet aggregation tests.
Conclusion:
The in vitro bleeding test provides a good alternative to the conventional methods commonly used for quality control of platelet concentrates.