[Rheumatological manifestations and HIV infection]

The spectrum of clinical manifestations in HIV infection has expanded considerably over the last few years. Several rheumatological syndromes have been associated with HIV infection such as Reiter's syndrome and other reactive arthritides, undifferentiated spondylarthropathy, but also HLA-B27-negative oligoarthritis, myopathy, Sjögren-like syndrome and vasculitis. Systemic lupus erythematosus and rheumatoid arthritis appear to be modified by the HIV infection. Further insight into interactions between HIV infection and these rheumatological syndromes will enlarge our epidemiological and pathogenetical understanding of the complex mechanisms involved. Awareness of such interactions is critical with respect to factors regarding both prognostic and therapeutic implications in the management of HIV infected patients.