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Related Experiment Videos

Ontogeny, pathology, oncology

V E Papaioannou1

  • 1Department of Pathology, Tufts University School of Medicine, Boston, MA 02111.

The International Journal of Developmental Biology
|March 1, 1993
PubMed
Summary
This summary is machine-generated.

Embryo-derived stem cells, including teratocarcinoma and embryonic stem cells, have revolutionized genetic manipulation. Research shows embryonic stem cells offer greater potential for gene targeting via homologous recombination.

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Area of Science:

  • Developmental Biology
  • Stem Cell Research
  • Cancer Research

Background:

  • Investigates the historical use of embryo-derived stem cells for genetic manipulation.
  • Explores parallels between normal embryonic development and neoplastic growth.
  • Compares the developmental potential of embryonal carcinoma (EC) stem cells and embryonic stem (ES) cells.