[Sclerodermia and nephro-urological tumors. Presentation of two cases]

The association between sclerodermia and malignant diseases is estimated around 3-7%. We present two cases of this disease concomitant to nephro-urological tumors. In one of these cases, we detected a hypernephroma in a patient with signs of florid sclerodermia, which did not disappear after nephrectomy and later showing evidence of metastasis. The other patient showed sclerodermiform signs developing quickly after transurethral resection of a vesical carcinoma. The highest incidence of associated neoplasias is observed in lung and breast cancers, hematological carcinoids and melanomas. Nephro-urological tumors are present in 0.3-0.5%.