Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Effect of increasing exchange volume or frequency on CAPD efficiency

J R Johnston1, J Bernardini, J Holley

  • 1Department of Medicine, University of Pittsburgh School of Medicine, Pennsylvania, USA.

Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis
|January 1, 1995
PubMed
Summary

Increasing peritoneal dialysis volume or frequency maintained KT/V despite declining residual renal function. However, higher KT/V targets may necessitate adjustments in both dialysate volume and exchange frequency for continuous ambulatory peritoneal dialysis (CAPD) patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiovascular risk factors in childhood obesity.

Journal of biological regulators and homeostatic agents·2020
Same author

Search for heavy resonances that decay into a vector boson and a Higgs boson in hadronic final states at <math> </math> <math></math>.

The European physical journal. C, Particles and fields·2020
Same author

Search for physics beyond the standard model in events with two leptons of same sign, missing transverse momentum, and jets in proton-proton collisions at <math> </math>.

The European physical journal. C, Particles and fields·2020
Same author

Search for new phenomena with the <math></math> variable in the all-hadronic final state produced in proton-proton collisions at <math> </math> <math></math>.

The European physical journal. C, Particles and fields·2020
Same author

Measurement of the triple-differential dijet cross section in proton-proton collisions at <math> </math> and constraints on parton distribution functions.

The European physical journal. C, Particles and fields·2020
Same author

Measurements of the associated production of a Z boson and b jets in pp collisions at <math> </math>.

The European physical journal. C, Particles and fields·2020

Area of Science:

  • Nephrology
  • Renal Medicine
  • Dialysis Technology

Background:

  • Continuous ambulatory peritoneal dialysis (CAPD) is a vital treatment for end-stage renal disease.
  • Optimizing dialysis clearance and maintaining adequate solute removal are crucial for patient outcomes.
  • Understanding the impact of different exchange strategies on dialysis efficiency is essential.

Purpose of the Study:

  • To assess the effects of increased dialysate volume, exchange frequency, and nocturnal exchange volume on dialysis urea and creatinine clearances (DUrCl, DCrCl) and KT/V in CAPD patients.
  • To investigate the relationship between these interventions and residual renal function (RRF).

Main Methods:

  • A study involving 20 CAPD patients undergoing 25 maneuvers over an average of 4.5 months.

Related Experiment Videos

  • Three groups were evaluated: increased overall exchange volume (Group A), increased exchange frequency (Group B), and increased nocturnal exchange volume (Group C).
  • Measurements included DUrCl, DCrCl, KT/V, and RRF before and after interventions.

    • Main Results:

    • Group A showed significant increases in DCrCl and DUrCl, with a non-significant decrease in RRF.
    • Group B demonstrated a 19% non-significant increase in DUrCl, accompanied by a significant decrease in RRF.
    • Group C exhibited no significant changes in dialysate clearances or RRF. Across all groups, KT/V remained stable despite changes in dialysis clearance and RRF decline.

    Conclusions:

    • Increasing dialysate volume or exchange frequency in CAPD can maintain KT/V as residual renal function declines.
    • Nocturnal exchange volume adjustments alone did not significantly alter dialysate clearances or RRF.
    • Achieving higher mandated KT/V values likely requires combined modifications in both dialysate volume and exchange frequency.