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Measles control in institutional settings

C S Kim1, H H Wright, E R Brenner

  • 1South Carolina Department of Mental Health, Columbia, USA.

Journal of the South Carolina Medical Association (1975)
|November 1, 1995
PubMed
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Screening pediatric psychiatric admissions for measles antibodies is useful. Most children had positive measles antibody tests, indicating prior immunity, but testing is cost-effective in institutions.

Area of Science:

  • Pediatric Psychiatry
  • Infectious Disease Immunology
  • Vaccinology

Background:

  • Measles outbreaks pose risks, especially in vulnerable populations.
  • Assessing immunity through antibody screening is crucial for vaccination strategies.
  • Pediatric psychiatric admissions represent a population requiring careful health evaluations.

Purpose of the Study:

  • To evaluate the utility of screening pediatric psychiatric admissions for measles antibodies.
  • To determine the need for Measles, Mumps, and Rubella (MMR) vaccine administration.
  • To analyze antibody prevalence based on demographics and psychiatric diagnoses.

Main Methods:

  • Screening of 314 pediatric psychiatric admissions over 11 months for measles antibodies.
  • Analysis of antibody test results in relation to sex, ethnicity, and psychiatric diagnosis.

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  • Evaluation of the cost-effectiveness of antibody testing in institutional settings.

    • Main Results:

    • 80.6% of children screened had positive measles antibody tests.
    • No significant sex differences in antibody prevalence were observed.
    • Caucasians showed a higher rate of negative antibody tests (18.2%) compared to African Americans (6.2%).
    • No correlation found between psychiatric diagnosis and measles antibody test results.
    • Adolescents frequently presented with negative or equivocal measles antibody tests, complicating interpretation.

    Conclusions:

    • Antibody screening is a valuable tool for assessing measles immunity in pediatric psychiatric admissions.
    • The findings support targeted MMR vaccination strategies based on antibody testing.
    • Antibody testing is cost-effective in institutional settings and may be in ambulatory settings.
    • Further research is needed to address challenges in interpreting antibody tests in adolescents.