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Synthesis and properties of cross-linked DNA duplexes
S I Antsypovich1, T S Oretskaya, E A Romanova
1Chemistry Department, Moscow State University, Russian Federation.
FEBS Letters
|January 15, 1996
Abstract:
A method has been devised to synthesize DNA duplexes with covalently connected strands. The structure of cross-linked duplexes was confirmed by a reaction with the restriction endonuclease AluI. The thermal stability of the resulting compounds was investigated.