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Updated: Aug 14, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
Malignancy associated changes in cervical smears: systematic changes in cytometric features with the grade of
M Guillaud1, A Doudkine, D Garner
1Cancer Imaging Department, British Columbia Cancer Agency, Vancouver, Canada.
Abstract:
For almost ten years. Malignancy Associated Changes have been consistently found by means of high resolution image analysis of apparently normal uterine cervix cells. The study was performed on normal intermediate cells randomly selected from 1850 cervical smear slides classified as negative, mild dysplasia, moderate dysplasia and severe dysplasia. Size and texture features, performed by the Cyto-Savant software, have shown significant monotonic changes with the grade of dysplasia. These findings indicate that the intensity of Malignancy Associated Changes are directly related to the severity of the adjacent lesions.
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