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Cell-to-cell contact and extracellular matrix

B M Gumbiner, K M Yamada

    Current Opinion in Cell Biology
    |October 1, 1995
    PubMed
    Summary

    This issue highlights current research in cell adhesion and transmembrane signaling. Discover advancements in understanding how cell-cell and cell-matrix contacts regulate tissue interactions.

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    Area of Science:

    • Cellular Biology
    • Biochemistry
    • Molecular Biology

    Background:

    • This issue presents a curated selection of current topics in cell adhesion and transmembrane signaling.
    • It covers both traditional and emerging areas within the field, offering a comprehensive overview.

    Discussion:

    • Focuses on the remarkable progress in elucidating the mechanisms of cell-cell and cell-matrix contacts.
    • Explores how these contacts establish and regulate physical adhesion.
    • Details the mediation of transmembrane signaling processes across various tissues.

    Key Insights:

    • Cell-cell and cell-matrix interactions are fundamental to tissue structure and function.
    • Understanding these contacts is crucial for deciphering cellular communication.
    • Significant advancements are being made in unraveling the molecular underpinnings of adhesion and signaling.

    Outlook:

    • Continued exploration of novel mechanisms in cell adhesion.
    • Further research into the role of transmembrane signaling in health and disease.
    • Integration of new findings into therapeutic strategies for tissue-related disorders.

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