Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Adhesion in cell migration

A Huttenlocher¹, R R Sandborg, A F Horwitz

¹Department of Cell and Structural Biology, University of Illinois, Urbana, 61801, USA.

Current Opinion in Cell Biology

|October 1, 1995

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Establishing an <i>ex vivo</i> porcine skin model to investigate the effects of broad-spectrum antiseptic on viable skin microbial communities.

mSphere·2025

Same author

Second harmonic generation microscopy in zebrafish.

Methods in cell biology·2016

Same author

Microfluidic device for simultaneous analysis of neutrophil extracellular traps and production of reactive oxygen species.

Integrative biology : quantitative biosciences from nano to macro·2016

Same author

Simple microfluidic device for studying chemotaxis in response to dual gradients.

Biomedical microdevices·2015

Same author

Spatial mapping of integrin interactions and dynamics during cell migration by image correlation microscopy.

Journal of cell science·2004

Same author

Extracellular matrix molecules regulate endothelial cell migration stimulated by lysophosphatidic acid.

Journal of thrombosis and haemostasis : JTH·2004

Same journal

Mechanosensing in immune cells: Implications for migration and beyond.

Current opinion in cell biology·2026

Same journal

Emerging role of organelles in cell migration.

Current opinion in cell biology·2026

Same journal

Nuclear adaptation in cell migration.

Current opinion in cell biology·2026

Same journal

Patterns in motion: Choreographing dynamic cell behaviours during tissue repair.

Current opinion in cell biology·2026

Same journal

Quo vadis reconstituted cell surfaces? Purpose and future perspectives for minimal systems of the cell plasma membrane.

Current opinion in cell biology·2026

Same journal

Nuclear determinants of mRNA and protein isoforms.

Current opinion in cell biology·2026

See all related articles

Cell migration relies on adhesive interactions, regulated by complex signaling. Integrins and rho family proteins are key, with ongoing research addressing remaining questions in cell motility.

Area of Science:

Cell Biology
Molecular Biology
Biochemistry

Background:

Adhesive interactions are crucial for cell migration.
Regulation involves intricate spatial and temporal signaling.
Integrin family proteins are central to these processes.

Purpose of the Study:

To review recent advances in understanding cell migration.
To highlight the role of integrins and rho family proteins.
To identify key unanswered questions in the field.

Main Methods:

Literature review of recent research.
Analysis of signaling pathways regulating cell adhesion.
Focus on integrin and rho family protein functions.

Main Results:

Related Experiment Videos

Significant progress in understanding growth factor-stimulated migration.
Advances in elucidating regulation of adhesive complex formation and breakdown.
Identification of key molecular players like integrins and rho family proteins.

Conclusions:

The field has made substantial progress in cell migration research.
Integrins and rho family proteins are critical regulators.
Further research is poised to answer remaining fundamental questions.