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Summary
Papillary eccrine adenoma, a rare sweat gland tumor, is typically found on extremities, especially in Black patients. This study confirms its benign nature, recommending surgical excision for effective treatment.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Papillary eccrine adenoma is a distinctive eccrine sweat gland tumor.
- Previously, its classification has sometimes been debated, with occasional consideration as malignant.
Purpose of the Study:
- To characterize papillary eccrine adenoma.
- To evaluate its clinical behavior and treatment outcomes.
- To establish its benign nature.
Main Methods:
- Retrospective study of 14 patients with papillary eccrine adenoma.
- Clinical follow-up of 11 patients for an average of 35 months post-excision.
- Histopathological examination of tumor characteristics.
Main Results:
- The majority of patients were Black, with tumors predominantly on distal extremities.
- No instances of metastasis were observed.
- One tumor recurred after initial excision but was successfully treated with re-excision, with no further recurrence in a subsequent 30-month follow-up.
- Microscopic features include duct-like structures with intraluminal papillations.
Conclusions:
- Papillary eccrine adenoma is a benign neoplasm.
- Surgical excision with clear surgical margins, confirmed by pathology, is the recommended treatment.
- Accurate histopathological recognition is crucial for diagnosis.