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Related Experiment Videos

A comparison between alternative and trade name glucose test strips

M J Lenhard1, G S DeCherney, R E Maser

  • 1Diabetes and Metabolic Diseases Center, Medical Center of Delaware, Wilmington 19806, USA.

Diabetes Care
|May 1, 1995
PubMed
Summary

Alternative glucose test strips can predict blood glucose levels but are generally less accurate and precise than manufacturer-approved strips. This study evaluated seven alternative glucose test strips for reliability across three glucose meters.

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Area of Science:

  • Biomedical Engineering
  • Clinical Chemistry
  • Medical Device Evaluation

Background:

  • Accurate blood glucose monitoring is crucial for diabetes management.
  • The availability of alternative glucose test strips offers potential cost savings but raises questions about reliability.
  • Evaluating the performance of these alternative strips against established methods is essential.

Purpose of the Study:

  • To assess the reliability and accuracy of seven different alternative glucose test strips.
  • To compare the performance of alternative test strips with manufacturer-approved (trade name) strips.
  • To determine the accuracy of alternative glucose test strips across various blood glucose ranges and with different glucose meters.

Main Methods:

  • Venous blood samples were collected from volunteers.

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  • Blood glucose levels were measured using laboratory analysis as a reference standard.
  • Seven alternative glucose test strips were tested on three different glucose meters (One Touch II, Glucometer II, Glucometer III).
  • Performance was evaluated using linear regression analysis and subgroup analysis based on glucose ranges.

    • Main Results:

    • Linear regression analysis showed R2 values ranging from 0.84 to 0.97 when comparing test strips to plasma glucose values.
    • Trade name strips and specific alternative strips (Quick Check, First Choice) demonstrated high accuracy and precision across all glucose ranges for certain meters.
    • Alternative strips were generally less accurate than trade name strips, with one exception (First Choice for Glucometer II).
    • All trade name test strips exhibited higher precision than the alternative strips.

    Conclusions:

    • Alternative glucose test strips can provide a prediction of laboratory blood glucose values.
    • However, alternative glucose test strips are generally not as accurate or precise as the trade name test strips.
    • The reliability of alternative glucose test strips varies depending on the specific strip, meter, and blood glucose range.