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Related Experiment Videos

Primary thrombocythaemia presenting as postpartum haemorrhage: a case report

Z Rashid1, N H Hamidah, A Othman

  • 1Department of Obstetrics and Gynaecology, Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia.

Journal of Obstetrics and Gynaecology (Tokyo, Japan)
|June 1, 1995
PubMed
Summary

A postpartum hemorrhage case in a young woman revealed primary thrombocythemia, a rare blood disorder. This condition, marked by high platelet counts and poor function, caused severe complications.

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Area of Science:

  • Obstetrics and Gynecology
  • Hematology
  • Internal Medicine

Background:

  • Postpartum hemorrhage (PPH) is a leading cause of maternal mortality.
  • Unexplained PPH requires thorough investigation into underlying hemostatic disorders.
  • Low forceps delivery is a known risk factor for obstetric complications.

Observation:

  • A young primigravida experienced severe PPH post-low forceps delivery without an obvious cause.
  • The patient presented with significant pallor and hepatosplenomegaly.
  • Multiple episodes of disseminated intravascular coagulation (DIC) occurred, necessitating a hysterectomy.

Findings:

  • Investigations revealed an extremely elevated platelet count.
  • Platelet aggregatory function was found to be poor.

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  • The clinical presentation and laboratory findings led to a diagnosis of primary thrombocythemia.

    • Implications:

    • Primary thrombocythemia can manifest with severe obstetric complications like PPH and DIC.
    • Early diagnosis of thrombocythemia is crucial for managing bleeding risks in pregnant and postpartum patients.
    • This case highlights the importance of considering hematological disorders in unexplained postpartum hemorrhage.