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Updated: Aug 9, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
C-cell distribution in ovine thyroid gland
1Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
Abstract:
The number and percentage of C-cells per unit area were investigated in 2-3-year-old sheep by an immunoperoxidase technique, using a digital-image analysis. C-cells were distributed throughout the thyroid lobes but were not present in either the isthmus or the superior and inferior poles of the thyroid. C-cells were more concentrated in the deep central region of the lobes and decreased gradually toward the periphery. There was a high correlation between the number and the percentage of C-cells per unit area of thyroid gland in sheep. Significant differences were not present between male and female sheep of 2-3 years of age.
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