Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Activity changes in early visual cortex reflect monkeys' percepts during binocular rivalry

D A Leopold1, N K Logothetis

  • 1Division of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA.

Nature
|February 8, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Brain Charts for the Rhesus Macaque Lifespan.

bioRxiv : the preprint server for biology·2024
Same author

Using non-invasive neuroimaging to enhance the care, well-being and experimental outcomes of laboratory non-human primates (monkeys).

NeuroImage·2020
Same author

Position paper on olfactory dysfunction.

Rhinology. Supplement·2018
Same author

Position paper on olfactory dysfunction.

Rhinology·2017
Same author

Corrigendum to "Can sliding-window correlations reveal dynamic functional connectivity in resting-state fMRI?" [NeuroImage 127 (2016) 242-256].

NeuroImage·2016
Same author

Can sliding-window correlations reveal dynamic functional connectivity in resting-state fMRI?

NeuroImage·2015

Binocular rivalry causes perceptual shifts without stimulus changes. Neuronal activity in visual areas V1, V2, and V4 correlates with these perception changes, challenging previous theories.

Area of Science:

  • Neuroscience
  • Visual Perception
  • Computational Neuroscience

Background:

  • Binocular rivalry involves alternating perception of dissimilar images presented to each eye.
  • Previous research suggested V1 neurons mediate rivalry, but evidence was limited.
  • Neuronal activity changes during rivalry reflect perceived, not physical, stimulus properties.

Purpose of the Study:

  • To investigate whether perception-related neural activity occurs in visual areas beyond MT during binocular rivalry.
  • To test the hypothesis that rivalry involves interactions between binocular neurons at multiple visual processing levels.

Main Methods:

  • Recorded single-unit activity in V1, V2, and V4 of monkeys.
  • Monkeys reported perceived orientation of orthogonal gratings during binocular rivalry.

Related Experiment Videos

  • Analyzed neuronal firing rates for correlation with perceptual dominance and suppression.

    • Main Results:

    • Many neurons, especially in V4, exhibited activity patterns tracking perceptual dominance.
    • These neurons were orientation-selective and responsive to input from both eyes.
    • Results did not support a V1-centric reciprocal inhibition model of rivalry.

    Conclusions:

    • Binocular rivalry likely involves interactions among binocular neurons across multiple visual cortical areas.
    • This suggests a distributed neural mechanism for resolving perceptual ambiguity.
    • Similar mechanisms may underlie other forms of multistable perception.