Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Jugulotympanic paragangliomas

R K Sur1, C V Levin, B Donde

  • 1Department of Radiation Therapy, University of the Witwatersrand, Johannesburg.

South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
|September 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endobronchial brachytherapy for metastasis from extrapulmonary malignancies as an effective treatment for palliation of symptoms.

Brachytherapy·2017
Same author

The influence of smoking on radiation-induced bystander signal production in esophageal cancer patients.

Environmental research·2016
Same author

2D∕3D registration algorithm for lung brachytherapy.

Medical physics·2013
Same author

Effects of tobacco smoking on cancer and cardiovascular disease in urban black South Africans.

British journal of cancer·2008
Same author

A phase I study of concurrent cisplatin chemotherapy in patients with carcinoma of the cervix receiving pelvic radiotherapy.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2006
Same author

Aggressive fibromatosis--impact of prognostic variables on management.

South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2006
Same journal

New hope for scar revision with a modified skin culture technique: a case report.

South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2026
Same journal

Median arcuate ligament syndrome without weight loss: a challenging diagnosis.

South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2026
Same journal

Complicated Amyand's hernia.

South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2026
Same journal

Management and outcomes of penetrating duodenal injuries: a retrospective cohort study from a level I trauma centre.

South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2026
Same journal

A 12-year review of equestrian related injuries at a major trauma centre in South Africa.

South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2026
Same journal

Cumulative incidence and management of enterocutaneous fistulas owing to laparotomy for penetrating abdominal trauma: a single centre experience.

South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2026
See all related articles

Radiotherapy offers effective long-term control and survival for glomus jugulotympanicum tumors. This treatment approach demonstrated positive outcomes in patients, with many remaining asymptomatic post-treatment.

Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Radiation Oncology

Background:

  • Glomus jugulotympanicum tumors are rare, slow-growing neoplasms arising from paraganglion cells in the temporal bone.
  • Treatment options historically included surgery and radiotherapy, with varying success rates and morbidity.
  • Optimal management strategies for these tumors remain a subject of ongoing research.

Purpose of the Study:

  • To evaluate the efficacy and long-term outcomes of radiotherapy in patients with glomus jugulotympanicum tumors.
  • To assess survival rates, local control, and symptom management following radiation treatment.
  • To review the clinical presentation, investigation methods, and literature regarding these tumors.

Main Methods:

  • Retrospective analysis of eleven patients diagnosed with glomus jugulotympanicum tumors between 1983 and 1993.

Related Experiment Videos

  • Nine patients received a full course of radiotherapy with doses ranging from 35 to 54 Gy.
  • Follow-up assessments were conducted to evaluate patient survival, symptom resolution, and cranial nerve function.

    • Main Results:

    • Four patients were assessed at 48 months post-treatment and were alive and asymptomatic.
    • In four additional patients, pain improved, though cranial nerve deficits persisted at follow-up (1-9 months).
    • One patient experienced mortality within one month of treatment initiation.

    Conclusions:

    • Radiotherapy can achieve long-term local control and improve survival in the management of glomus jugulotympanicum tumors.
    • The findings support radiotherapy as a viable treatment option, particularly for achieving symptom relief and prolonging survival.
    • Further investigation into optimal radiotherapy techniques and patient selection is warranted.