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Multiple periorbital cutaneous myxomas progressing to scleromyxedema
N M Craig1, A M Putterman, R K Roenigk
1Department of Dermatology, Northwestern University Medical School, Chicago, IL 60611, USA.
Journal of the American Academy of Dermatology
|May 1, 1996
Summary
Multiple periorbital myxomas can indicate a rare condition called scleromyxedema. This case highlights the importance of recognizing associated systemic symptoms and treating deep venous thrombosis effectively.
Area of Science:
- Dermatology
- Oncology
- Hematology
Background:
- Myxomas are rare cutaneous tumors.
- Associated abnormalities include atrial myxomas, endocrine issues, and bone malformations.
Observation:
- A 38-year-old man presented with multiple periorbital myxomas.
- He developed myalgias, fatigue, and diffuse cutaneous involvement.
- An associated left subclavian deep venous thrombosis was diagnosed.
Findings:
- The patient's symptoms were consistent with scleromyxedema.
- Cyclophosphamide therapy led to a positive response.
Implications:
- This case underscores the systemic implications of cutaneous myxomas.
- Early recognition and comprehensive management are crucial for patients with scleromyxedema.
- Cyclophosphamide shows efficacy in treating this rare condition.