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Invasive aspergilloma of the frontal base causing internal carotid artery occlusion
1Department of Neurosurgery, Hiroshima University School of Medicine, Japan.
Background:
Aspergilloma of the nasal cavity or paranasal sinuses rarely extends through the skull base into the intracranial space.
Patient:
The patient was a 79-year-old man in a nonimmunosuppressive state who had an invasive aspergilloma of the base of the frontal lobe.
Clinical Course:
The patient, whose initial symptom was a visual disturbance, eventually developed an occlusion of the right internal carotid artery and died. The diagnosis was established by a transsphenoidal biopsy.
Conclusions:
A rare case of invasive aspergilloma of the frontal base is described with emphasis on the findings of low-intensity mass on the T2-weighted magnetic resonance imaging (MRI). The prognosis in this disease is very poor. Early diagnosis and surgical treatment, combined with postoperative antifungal drug therapy, would have improved the outcome.