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Recovery in geriatric depression

G S Alexopoulos1, B S Meyers, R C Young

  • 1Cornell University Medical College, White Plains, NY, USA.

Archives of General Psychiatry
|April 1, 1996
PubMed
Summary
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Elderly patients with major depression show recovery rates similar to younger adults. Late age at onset predicts slower recovery in older individuals, while treatment intensity may decline prematurely.

Area of Science:

  • Geriatric psychiatry
  • Clinical psychology
  • Neuroscience

Background:

  • Depression course is influenced by clinical factors like age at onset, disability, and social support.
  • Understanding recovery predictors in elderly depression is crucial for effective treatment.

Purpose of the Study:

  • To investigate the recovery timetable for elderly patients with major depression.
  • To identify factors predicting recovery in this demographic.

Main Methods:

  • Followed 63 elderly and 23 younger patients with depression for an average of 18.2 months.
  • Used the Schedule for Affective Disorders and Schizophrenia and the Longitudinal Follow-up Interval Examination for diagnosis and recovery assessment.

Main Results:

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  • Elderly patients had similar recovery rates to younger patients.
  • Late age at onset was the strongest predictor of slow recovery in the elderly.
  • Treatment intensity declined in elderly patients before recovery, and prior to relapse prevention.

Conclusions:

  • Geriatric depression does not necessarily have a worse outcome than in younger adults.
  • Late-life onset depression may carry a higher risk of chronicity.
  • Antidepressant treatment intensity may decrease prematurely, potentially impacting recovery and relapse prevention.