Related Experiment Video
Updated: Aug 6, 2026
11:51
An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
Published on: February 10, 2014
Behavior of calcium phosphate coatings with different chemistries in bone
H W Denissen1, C P Klein, L L Visch
1Department of Oral Function and Implantolgy, Academic Center for Dentistry Amsterdam, The Netherlands.
The International Journal of Prosthodontics
|March 1, 1996
Summary
New fluorapatite and heat-treated hydroxyapatite coatings for dental implants show stable thickness, unlike current hydroxyapatite coatings. These advanced coatings offer comparable bone bonding and biocompatibility for improved implant longevity.
Area of Science:
- Biomaterials Science
- Dental Implantology
- Orthopedic Research
Background:
- Calcium phosphate ceramic coatings, particularly hydroxyapatite (HA), enhance dental implant osseointegration.
- Current HA coatings can degrade over time, leading to thinning and potential loss of implant stability.
- Need for more durable coatings that maintain osseointegration benefits.
Purpose of the Study:
- To compare the in-bone performance of novel fluorapatite (FA) and heat-treated hydroxyapatite (HA) coatings against standard HA coatings.
- To evaluate the long-term stability and biocompatibility of these advanced coatings on dental implants.
Main Methods:
- Experimental study in dogs using dental implants coated with FA, heat-treated HA, and standard HA (control).
- Histological evaluation of bone response and coating integrity over a 24-month observation period.
- Assessment of coating thickness changes and bone condensation around the implants.
Main Results:
- All coatings demonstrated excellent biocompatibility and strong bone bonding, with evident bone condensation.
- Standard HA coatings showed significant thinning due to material loss over 24 months.
- FA and heat-treated HA coatings maintained stable thickness with minimal degradation throughout the study period.
Conclusions:
- Fluorapatite and heat-treated hydroxyapatite coatings offer superior long-term coating stability compared to conventional HA coatings.
- These advanced coatings provide comparable osseointegration and biocompatibility, addressing the degradation issue of current HA coatings.
- FA and heat-treated HA coatings represent promising alternatives for enhanced dental implant durability and performance.
Related Concept Videos
01:40Bone Remodeling
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
01:18The Bone Matrix
Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in acid or...
01:31Essential Minerals for Bone Health
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
01:17Hormones and Bone Tissue
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
01:31Bone Remodeling and Repair
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
01:27Roles of Electrolytes: Calcium and Phosphate
Calcium and phosphate are essential electrolytes in the human body, with calcium being the most abundant mineral. Around 99% of the body's calcium is stored in the skeleton and teeth, forming a crystal lattice of mineral salts in combination with phosphates. Calcium plays crucial roles in various bodily functions such as blood clotting, neurotransmitter release, muscle tone maintenance, and nervous and muscle tissue excitability.
The calcium concentration in blood plasma is primarily regulated...
The calcium concentration in blood plasma is primarily regulated...