Related Experiment Video
Updated: Dec 27, 2025

08:05
Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice
Published on: June 29, 2022
3.3K
Electromechanical delay in the left atrium as a consequence of interatrial block
1Cardiology Division, St. Vincent Hospital, Worcester, Massachusetts, 01604, USA.
The American Journal of Cardiology
|May 15, 1996
Summary
Interatrial block significantly delays left atrial mechanical activity. This study compared electromechanical intervals in patients with interatrial block to controls, revealing significant impacts on cardiac function.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiac Physiology
Background:
- Interatrial block (IAB) is a condition affecting the electrical conduction between the atria.
- Understanding its impact on atrial mechanical function is crucial for assessing cardiac performance.
- Previous research has focused on electrical conduction, with less emphasis on mechanical consequences.
Purpose of the Study:
- To investigate the effects of interatrial block on left atrial mechanical activity.
- To compare electromechanical intervals and ventricular filling onsets between patients with IAB and healthy controls.
- To elucidate the relationship between IAB and delayed atrial mechanical function.
Main Methods:
- Measurement of right and left atrial electromechanical intervals.
- Assessment of the onsets of active right and left ventricular filling.
- Comparison of these parameters in patients diagnosed with interatrial block versus a control group.
Main Results:
- Patients with interatrial block exhibited significantly delayed left atrial mechanical activity compared to controls.
- Specific electromechanical intervals were prolonged in the IAB cohort.
- Onsets of active ventricular filling showed alterations in patients with IAB.
Conclusions:
- Interatrial block is associated with a significant delay in left atrial mechanical function.
- These findings highlight the mechanical repercussions of conduction abnormalities within the atria.
- Further research may explore the clinical implications of delayed atrial mechanics in IAB.
Related Concept Videos
The Cardiac Cycle
97.0K
The heart beats rhythmically in a sequence called the cardiac cycle—a rapid coordination of contraction (systole) and relaxation (diastole).
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and...
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and...
97.0K
Disturbances in Heart Rhythm
2.3K
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
2.3K
Dysrhythmias IV: Characteristics of Bradyarrhythmias
386
Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
386
Mitral Stenosis I: Introduction
313
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
313
Chambers of the Heart
9.4K
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Deoxygenated blood from the body is received in the right...
9.4K
Mechanism of Cardiac Arrhythmias
1.5K
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
1.5K

