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[Vision disorders to vascular dysregulation]
F Flammer1, J Messerli, I Haefliger
1Universitätsaugenklinik Basel.
Therapeutische Umschau. Revue Therapeutique
|January 1, 1996
Summary
Arterial sclerosis can cause eye infarctions and transient perfusion issues due to vascular dysregulation. These conditions may contribute to serious eye diseases like glaucoma and optic nerve apoplexy.
Area of Science:
- Ophthalmology
- Vascular Biology
- Neurology
Context:
- Arterial sclerosis is a known cause of organ infarction, including the eye.
- Vascular dysregulation can lead to reversible perfusion disturbances in the eye.
- These disturbances are often transient and unnoticed but can contribute to disease pathogenesis.
Purpose:
- To examine the role of vascular dysregulation in ocular diseases.
- To investigate the link between arterial sclerosis, perfusion disturbances, and specific eye conditions.
- To understand the pathogenesis of ocular vasospastic syndrome, migraine, glaucoma, optic nerve apoplexy, and vein thrombosis.
Summary:
- Eye infarctions result from arterial sclerosis, with classic risk factors applicable.
- Reversible perfusion disturbances due to vascular dysregulation are frequent, often causing minor, transient functional failures.
- In rarer instances, vascular dysregulation contributes to ocular vasospastic syndrome, migraine, glaucoma, optic nerve apoplexy, and vein thrombosis.
Impact:
- Highlights the significance of vascular health in preventing ocular pathologies.
- Provides insights into the mechanisms underlying various eye diseases.
- Emphasizes the need for recognizing and managing vascular dysregulation in ophthalmology and neurology.