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Resection of malignant primary liver tumors
R F Holbrook1, K Koo, J A Ryan
1Department of Surgery, Virginia Mason Medical Center, Seattle, Washington 98111, USA.
American Journal of Surgery
|May 1, 1996
Summary
Surgical resection offers the best chance for cure in primary liver cancer patients. Liver cancer surgery outcomes demonstrate significantly improved survival rates compared to non-surgical management.
Area of Science:
- Hepatobiliary surgery
- Surgical oncology
- Gastroenterology
Background:
- Malignant primary liver tumors present significant surgical challenges.
- Surgical resection is the primary curative treatment for liver cancer.
- This study reviews a single surgeon's 13-year experience with liver tumor resections.
Purpose of the Study:
- To evaluate the outcomes of surgical resection for primary liver cancer.
- To assess the efficacy of liver tumor resection as a treatment modality.
Main Methods:
- Retrospective review of patients diagnosed with primary liver cancer from July 1982 to June 1995.
- Analysis of 46 resections performed on 43 patients by a single surgeon.
Main Results:
- 43 patients underwent 46 resections for primary liver cancer (hepatomas, cholangiocellular carcinomas, etc.).
- Major complications occurred in 26% of patients, with a 7% 30-day perioperative death rate.
- Patients undergoing resection had a median survival of 21 months, significantly longer than those not resected (median < 6 months). 1-, 2-, 3-, and 5-year survival rates were 57%, 52%, 40%, and 33% respectively.
Conclusions:
- Surgical resection is an effective treatment for primary liver cancer.
- Resection offers superior survival outcomes compared to non-surgical management for liver cancer patients.