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Comparative toxicity in earthworms Eisenia fetida and Lumbricus terrestris exposed to cadmium nitrate using

L C Fitzpatrick1, J F Muratti-Ortiz, B J Venables

  • 1Environmental Effects Research Group, Division of Environmental Sciences, Department of Biological Sciences, University of North Texas, Denton, Texas 76203, USA.

Bulletin of Environmental Contamination and Toxicology
|July 1, 1996
PubMed
Abstract

No abstract available in PubMed .

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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...

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