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Updated: Aug 6, 2026

Quantitative Analyses of all Influenza Type A Viral Hemagglutinins and Neuraminidases using Universal Antibodies in Simple Slot Blot Assays
Published on: April 4, 2011
Human CD4+ T-cell recognition of influenza A virus hemagglutinin after subunit vaccination
C M Gelder1, J R Lamb, B A Askonas
1Infection and Immunity Section, Department of Biology, Imperial College of Science, Technology and Medicine, London, United Kingdom.
Abstract:
We have examined human CD4+ T-cell recognition of influenza A/Beijing/32/92 (H3N2) virus hemagglutinin following influenza virus HANA subunit vaccination. CD4+ T-cell repertoires were dominated by recognition of epitopes located in conserved regions of the molecule, in a major histocompatibility complex class II haplotype-dependent manner, analogous to that observed following natural infection.
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