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Updated: Aug 8, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
An unusual source for an outbreak of methicillin-resistant Staphylococcus aureus on an intensive therapy unit
S Cotterill1, R Evans, A P Fraise
1Microbiology Department, City Hospital NHS Trust, Birmingham, UK.
Abstract:
During a four-month period, six patients on an intensive therapy unit became colonized or infected with methicillin-resistant Staphylococcus aureus (MRSA). Four of these patients were colonized by the Epidemic MRSA strain 15 (EMRSA 15). The outbreak was characterized by the fact that all four of these patients were nursed in the same bed on the unit before acquisition of the organism. Investigation of the outbreak led the authors to believe that the source of the MRSA may have been the exhaust ducting of the adjacent isolation room ventilation system which allowed the organisms to enter the unit via a partially open window positioned above that particular bed. The cycle was broken once the ventilation system was repaired and the window above the bed was properly sealed.
Insights
An intensive care unit outbreak of methicillin-resistant Staphylococcus aureus (MRSA) was linked to contaminated ventilation systems. Prompt repair of the ventilation and sealing a window stopped the spread of this dangerous hospital-acquired infection.
Area of Science:
- Infectious Diseases
- Hospital Epidemiology
- Microbiology
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant threat in healthcare settings, particularly intensive therapy units.
- Controlling the spread of hospital-acquired infections (HAIs) is crucial for patient safety and effective healthcare management.
Observation:
- An outbreak of MRSA, including the EMRSA 15 strain, occurred over four months in an intensive therapy unit.
- Four patients with EMRSA 15 were all nursed in the same bed prior to infection or colonization.
Findings:
- Investigation suggested the MRSA originated from exhaust ducting of an adjacent isolation room's ventilation system.
- Contaminated air entered the unit through a partially open window above the affected bed.
Implications:
- Environmental contamination, specifically ventilation systems, can be a source of MRSA transmission in hospitals.
- Interventions like repairing ventilation and sealing windows are effective in breaking MRSA transmission cycles.
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