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Updated: Aug 19, 2026

Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
[Congenital leukemia--personal experience]
N Konstantinidis1, G Konstantinidis, A Ristivojević
1Centar za hemato-onkologiju, Institut za zdravstvenu zastitu dece i omladine, Medicinski fakultet, Novi Sad.
Abstract:
Congenital leukemia is a very rare form of acute leukemia and up to now more than 100 well documented cases have been published. Symptoms and signs of the disease may be faintly differentiated and be a differential diagnostic problem for a long period of time in comparison to other common diseases of the newborn. This is a case report on two newborns with congenital leukemia. It was an acute non-lymphoblastic leukemia in the first case, and acute lymphoblastic leukemia in the second. In both cases there were nonspecific manifestations of the disease (no weight gaining, hemorrhagic enterocolitis). In both cases polyhemotherapeutic protocols were performed. In the first case only partial remission occurred and death occurred during the hemathologic recidive of the disease. In the second case, 15 months after the diagnose of congenital leukemia has been established, complete remission is in course.
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