Related Experiment Video
Updated: Oct 12, 2026

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
Published on: April 5, 2011
Clinical evaluation of the poisoned patient and toxic syndromes
1Department of Emergency Medicine, Johns Hopkins Hospital, Baltimore, MD 21287-3080, USA. jaydoc@welchlink.welch.jhu.edu
Abstract:
Poisonings and toxic exposures are prominent causes of morbidity and mortality in patients that present to the emergency department. The American Association of Poison Control Centers, in its 1994 annual report, cites a 10% increase in the number of reported cases of poison exposure. The clinical evaluation and management of such patients remain challenging. Few specific antidotes are available for the many potential poisonings that occur annually. Rapid stabilization, resuscitation, and recognition of major toxic syndromes, along with appropriate utilization of laboratory testing, guide the clinician in the treatment of such patients.
Related Concept Videos
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Prevention of Further Absorption of Poison
Drug Toxicity: Overview
Toxidromes: Clinical Features
Pharmaceutical Poisoning: Potential Scenarios
Pharmaceutical Poisoning: Treatment Strategies

