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[Intermittent Romano-Ward syndrome]
J Tomcsányi1, B Merkely, F Solti
1Országos Korányi TBC és Pulmonológiai Intézet, Budapest.
Orvosi Hetilap
|March 17, 1996
Summary
Intermittent long QT syndrome is difficult to diagnose and can be fatal, especially with certain antiarrhythmic drugs. Holter monitoring is crucial for diagnosing this condition, as shown in two case studies.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Intermittent long QT syndrome presents diagnostic challenges.
- It carries a risk of fatal arrhythmias, particularly with Class IA antiarrhythmic drugs.
Observation:
- Two patients experienced syncope and dizziness, indicative of undiagnosed long QT syndrome.
- Symptoms included a prior episode of "quinidine syncope" in one patient.
Findings:
- Holter monitoring successfully diagnosed intermittent long QT syndrome in both cases.
- Monophasic action potential recordings revealed early afterdepolarizations.
Implications:
- This study highlights the diagnostic utility of Holter monitoring for intermittent long QT syndrome.
- Early diagnosis and management are critical to prevent fatal outcomes.