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[Daily defined doses of parkinsonian drugs in Alcoi]
R Manzanares1, J Matías-Guiu, R Provencio
1Departmento de Medicina y Psiquiatria, Universidad de Alicante.
Background:
Some authors have suggested that the use of DDD (defined daily doses) of L-dopa may be useful as an indicator of the frequency of Parkinson's disease.
Aim:
To determine the measurement for L-dopa and selegiline in Alcoi.
Material And Methods:
We have obtained the intakes for L-dopa and selegiline between January and December, 1990 and we have calculated the DDD/1,000 inhab/day.
Results:
During the study period, we have found that the mean intakes were 18,000.969 mg and 53,800 mg for L-dopa and selegiline, respectively. And so, the L-dopa intake in Alcoi was 0.60 DDD/ 1,000 inh, and the selegiline intake was 0.21 DDD/1,000 inh.
Discussion:
Comparing the other data of the literature, specially in scandinavian countries, the obtained intake for L-dopa was low, and that could indicate that the frequency of the disease in Alcoi was lower.