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Unusual tumors causing extrahepatic portal venous obstruction
B C Sharma1, V A Saraswat, R K Dhiman
1Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Summary
Extrahepatic portal vein obstruction can occur with gastric tumors, leading to bleeding varices. Direct vascular infiltration by leiomyosarcoma or lymphoma complicated management due to portal hypertension.
Area of Science:
- Gastroenterology
- Oncology
- Vascular Surgery
Background:
- Extrahepatic portal vein obstruction is typically linked to liver, bile duct, and pancreatic malignancies.
- Portal vein obstruction can lead to serious complications such as variceal bleeding.
Observation:
- Two cases of extrahepatic portal vein obstruction are presented.
- One case involved gastric leiomyosarcoma, the other Non-Hodgkin's lymphoma.
Findings:
- Both cases presented with gastric variceal bleeding due to portal vein obstruction.
- Portal vein block resulted from direct vascular infiltration by the tumors.
- Portal hypertension developed in both patients, complicating clinical management.
Implications:
- This highlights rare causes of portal vein obstruction beyond typical hepatic malignancies.
- Direct tumor infiltration of the portal vein requires careful consideration in managing gastrointestinal bleeding and portal hypertension.
- Understanding these associations is crucial for accurate diagnosis and treatment planning in oncology and gastroenterology.