[Comparative study on hepatic and intestinal pathological changes in different animals with schistosomiasis japonica]

The pathological changes of livers and intestines were compared among cats, dogs and rabbits infected with Schistosoma japonicum cercariae for three months. The resuults showed that the most serious lesions were seen in rabbits while the slightest were in cats. The granulomatous response was more distinct in livers than in intestines in all the three animals. The increment ratio of egg granuloma in livers was 3.52, 2.64 and 1.81 in rabbits, dogs and cats, respectively. The eggs were deposited singly or in strings, few granuloma formation was observed in the intestines. In addition to inflammatory infiltration, swelling and/or dropping of mucosa the gland destruction and ulcer were also observed in the mucosa. The investigation demonstrated that pathological lesions varied in different animal species.