Related Experiment Videos
Cytarabine release from alpha, beta-poly (N-hydroxyethyl)-DL-aspartamide matrices cross-linked through
G Spadaro1, C Dispenza, G Giammona
1Dipartimento di Ingegneria Chimica dei Processi e Materiali, Università di Palermo, Palermo, Italy.
Biomaterials
|May 1, 1996
Abstract:
alpha, beta-Poly (N-hydroxyethyl)-DL-aspartamide solutions were cross-linked through gamma-radiation and the systems obtained were tested as matrices for drug sustained release, using cytarabine as model drug. We performed the characterization of the cross-linked polymer, both drug-loaded and unloaded. through water swelling measurements, scanning electron microscopy and X-ray analysis. Finally, we investigated the in vitro release behaviour of cytarabine.