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Blood group chimerism in human multiple births is not rare
B A van Dijk1, D I Boomsma, A J de Man
1Blood Transfusion Department, University Hospital St. Radboud, Nijmegen, Netherlands.
American Journal of Medical Genetics
|January 22, 1996
Abstract:
Twin blood group chimerism seems to be very rare in humans. The 30-40 previously reported cases usually were found by mere coincidence during routine blood grouping in hospitals or blood banks. Usually in these cases frank blood group mixtures of, for example, 50/50%, 25/75%, or 5/95% at most were seen. Smaller percentages are very difficult to notice during routine work-up. Using a sensitive fluorescence technique (sensitivity > 0.01%) we detected blood group chimerism in 32/415 (8%) twin pairs and 12/57 (21%) triplet pairs, respectively, which is a higher incidence than reported previously.