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[Melkersson-Rosenthal syndrome treated by thalidomide. 2 cases]
1Clinique Dermatologique, Hôpital Charles-Nicolle, Rouen.
Annales De Dermatologie Et De Venereologie
|January 1, 1995
Abstract
Introduction:
Treatment of Melkersson-Rosenthal syndrome (MRS) remains uncertain. Two cases of MRS treated with thalidomide are described.
Case Report:
Two patients with cheilitis granulomatosa and recurrent facial edema have been treated with thalidomide (100 mg daily) for 3 and 6 months respectively. The efficacy of thalidomide was complete clinically and histologically in one case. In the second one, thalidomide suppressed attacks of facial edema and reduced lip swelling.
Comments:
These cases suggest a therapeutic effect of thalidomide in MRS.