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[Mibelli porokeratosis in 2 brothers]
H G Yedomon1, F Do Ango-Padonou
1Service de Dermatologie, Centre National Hospitalier et Universitaire (CNHU), Cotonou Bénin.
Introduction:
Mibelli's porokeratosis is uncommon in black persons. We report two brothers who had two different clinical presentations.
Case Report:
The brothers were seen at the ages of 16 and 19 years. Both had Mibelli's porokeratosis, one with a papulo-verruciform presentation located on the scrotum, the anus, the gluteal area and the back of the hand, and the other with a superficial disseminated eruption involving the face and the forearm.
Discussion:
The incidence of Mibelli's porokeratosis in the black population at Cotonou is approximately 0.3 per 10.000. The presence of the disease in two uterine brothers confirms the monogenic and familial nature of Mibelli's porokeratosis. Dominant transmission cannot be easily demonstrated when the parents of the patients are phenotypically healthy.