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Overweight, gender and knee osteoarthritis
P Manninen1, H Riihimäki, M Heliövaara
1Department of Community Health and General Practice, University of Kuopio, Finland. Pirjo.Manninen@messi.uku.fi
Summary
Older age, female gender, and higher body mass index (BMI) are significant risk factors for disabling knee osteoarthritis. Overweight significantly increases the risk of developing knee osteoarthritis.
Area of Science:
- Epidemiology
- Orthopedics
- Public Health
Background:
- Knee osteoarthritis is a leading cause of disability.
- Risk factors for disabling knee osteoarthritis require further investigation.
Purpose of the Study:
- To examine the association between age, gender, body mass index (BMI), and the incidence of disabling knee osteoarthritis.
- To identify independent predictors of disabling knee osteoarthritis in a farming population.
Main Methods:
- A 10-year follow-up study involving 6647 farmers aged 40-64 years.
- Record linkage with the Social Insurance Institution's register to identify disability pensions.
- Review of medical certificates to determine incident cases of disabling knee osteoarthritis.
Main Results:
- Age, female gender, and BMI were independent predictors of disabling knee osteoarthritis.
- A linear relationship was observed between BMI and knee osteoarthritis incidence (RR 1.4 per SD increase).
- Women had significantly higher adjusted relative risks for unilateral and bilateral knee osteoarthritis compared to men.
Conclusions:
- Overweight is a strong risk factor for disabling knee osteoarthritis.
- Female gender is associated with a substantially higher risk of disabling knee osteoarthritis.
- Public health initiatives should focus on weight management and gender-specific prevention strategies for knee osteoarthritis.