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Pathophysiology of ion channel mutations

M T Keating¹, M C Sanguinetti

¹Howard Hughes Medical Institute, University of Utah, Salt Lake City 84112, USA.

Current Opinion in Genetics & Development

|June 1, 1996

Abstract:

The past year has seen significant advances in our understanding of ion channel disorders. The highlights of these advances include a detailed delineation of the molecular mechanisms underlying inherited cardiac arrhythmias and the discovery that ion channel mutations can contribute to neural development and neurodegeneration.

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