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Hematologic changes after two exposures to 6.7 ATA air at three-day intervals
Summary
Repeated hyperbaric exposures, like deep sea diving, can alter hematologic parameters, particularly affecting platelets and clotting. Even standard diving procedures may not be entirely safe, with effects accumulating over time.
Area of Science:
- Physiology
- Hematology
- Hyperbaric Medicine
Background:
- Diving exposes humans to increased ambient pressure.
- Understanding hematologic responses to diving is crucial for diver safety.
Purpose of the Study:
- To investigate hematologic changes in human subjects under simulated diving conditions.
- To assess the cumulative effects of repeated hyperbaric exposures.
Main Methods:
- Subjects underwent simulated dives to 188 fswg (6.7 ATA) using compressed air.
- Hematologic parameters were monitored before, during, and up to one week after dives.
- Repeated dive protocols were employed with serial hematologic assessments.
Main Results:
- Single dives showed minor platelet factor alterations.
- Repeated dives resulted in eosinopenia and prolonged clotting times.
- Platelet depletion, clumping, and elevated megathrombocytes persisted post-dive.
- Latent hemodilution was observed 3-5 days after the second dive.
Conclusions:
- Repeated hyperbaric exposures have additive hematologic effects.
- Standard diving procedures may carry risks and are not entirely innocuous.
- Further research into safe diving protocols is warranted.