Bone tissue response to commercially pure titanium implants blasted with fine and coarse particles of aluminum oxide

The present study compares the bone response to commercially pure titanium screws with two different degrees of surface roughness. Implants blasted with 25- and 250-micron particles of aluminum oxide were placed in rabbit tibiae after the surface roughness of the implants had been measured. After 4 weeks, there was a significantly higher bone-to-metal contact for implants blasted with 25-micron particles compared to those blasted with 250-micron particles. The present study indicates that a highly increased surface roughness compared to a moderately increased one is a short-term disadvantage for bone tissue.