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Updated: Oct 1, 2026
Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
Lymphoid involvement in a patient with acute myeloid leukemia: a direct phenotypic and genotypic study of single
W El-Rifai1, M L Larramendy, T Ruutu
1Department of Medical Genetics, University of Helsinki, Finland.
Abstract:
Lymphoid involvement in acute myeloid leukemia (AML) was studied using the morphology-antibody-chromosome (MAC) combination technique in one patient. The chromosomal aberration, trisomy 8, was demonstrated in AML blasts, glycophorin A-positive erythroblasts, and CD3- and CD20/22-positive small lymphocytes. This suggests that in this patient even lymphocytes belonged to the leukemic clone.
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